Buspirone

Buspirone (Ansial^®; Ansiced^®; Anxiron^®; Axoren^®; Bespar^®; Buspar^®; Buspimen^®; Buspinol^®; Buspisal^®; Narol^®) is an anxiolytic drug. It generally is considered to have a significantly lower addiction potential compared to other drugs commonly prescribed for anxiety, especially benzodiazepine medications. Furthermore, it is non-sedating. It is thought to act by interfering with the function of the neurotransmitter serotonin in the brain, particularly by serving as a 5-HT1A receptor partial agonist. Bristol-Myers Squibb gained FDA approval for Buspirone in 1986. The drug went generic in 2001.

It is also useful as an augmenting agent, for the treatment of depression, when added to SSRI's (selective serotonin reuptake inhibitors)