Chlorphenamine

Chlorphenamine
(3RS)-3-(4-chlorophenyl)-N,N-dimethyl- 3-(pyridin-2-yl)propan-1-amine
CAS number 132-22-9	ATC code  ?
Chemical formula	C16H19ClN2
Molecular weight	274.8
Bioavailability	25-50%
Metabolism	hepatic
Elimination half-life	6.3-23.1 hours
Excretion	renal
Pregnancy category	Category A (Australia)
Legal status	Schedule 3 (Australia)
Routes of administration	oral

Chlorphenamine (INN) or chlorpheniramine (USAN, former BAN), commonly marketed as its salt chlorphenamine maleate (CPM), is first-generation antihistamine used in the prevention of the symptoms of allergic conditions such as rhinitis and urticaria.

CPM is one of the main ingredients in many OTC allergy medications, such as Coricidin Cough & Cold (or CCC). Many people use Coricidin recreationally for the dextromethorphan content; however, this is strongly recommended against. In high doses, chlorpheniramine maleate can cause severe allergic reactions and has been linked to at least twelve deaths in the United States.

External links

• The Coricidin Harm Reduction Project